3,5-Dichlorobenzoyl Chloride (3,5-DCBC): Key Intermediate for Agrochemicals and Pharmaceuticals
CAS No.: 2905-62-6
3,5-Dichlorobenzoyl chloride (3,5-DCBC) is a high-value aromatic acid chloride intermediate.
It is used as a key building block in the manufacture of high-performance herbicides, active pharmaceutical ingredients (APIs) and advanced specialty chemicals.
Royalchem, a Spain-based trading company, is a trusted global supplier of 3,5-DCBC. We supply this critical intermediate to leading agrochemical and pharmaceutical companies across Europe, South America and other key markets. Our focus on quality and regulatory compliance helps ensure reliable performance in both large-scale production and innovative R&D projects.
Product Data
Product name: 3,5-Dichlorobenzoyl chloride (3,5-DCBC)
CAS No.: 2905-62-6
Appearance: Colorless to pale yellow liquid or low-melting solid
Melting point: 24–28 °C
Why 3,5-DCBC Is Essential
3,5-DCBC is a value-added intermediate whose reactivity comes from its acyl chloride group.
This highly reactive functionality makes 3,5-DCBC an excellent starting point for building more complex molecules in several high-value chemical sectors, especially agrochemicals and pharmaceuticals.
Main Applications
1. Agrochemicals: Link to Propyzamide
The most important use of 3,5-DCBC is as a key intermediate in the synthesis of the herbicide propyzamide (pronamide). Propyzamide is widely used in modern agriculture, particularly for controlling weeds that are resistant to other herbicides.
Key markets: Protection of crops such as oilseed rape (canola), lettuce and various vegetables.
Strategic importance: As resistance to traditional herbicides increases, demand for propyzamide is expected to grow. This makes 3,5-DCBC a strategically important intermediate for global crop protection and food supply.
2. Pharmaceutical Industry: A Versatile Building Block
In pharmaceutical synthesis, 3,5-DCBC is used to construct complex molecules. Introducing the 3,5-dichlorobenzoyl fragment into a drug candidate can:
Extend the half-life of the drug in the body.
Improve absorption and overall bioavailability.
Enhance the ability of the active ingredient to reach its target site.
Typical areas of use include:
Pain management: Development of new analgesics and headache treatments.
Advanced therapies: Key intermediate in selected drug candidates, including molecules approved by major regulatory agencies such as the FDA.
Metabolic and CNS disorders: Used in compounds aimed at central nervous system (CNS) targets and metabolic pathways.
3. Specialty Chemicals and Materials
3,5-DCBC is also used to produce a range of high-performance materials, including:
Durable, weather-resistant dyes and pigments.
Specialty chemicals for imaging and photographic applications.
Polymer additives and intermediates for liquid crystal and other advanced materials.
Industry-Grade Quality Specifications
Royalchem supplies 3,5-DCBC that meets strict purity standards for both agrochemical and pharmaceutical applications. Tight impurity control helps ensure that your downstream syntheses are efficient, reproducible and straightforward to validate.
Main specification:
Critical impurity control (maximum limits):
Positional isomers (total): ≤ 0.50 %
2,5-DCBC: 0.20 %
2,4-DCBC: 0.10 %
3,4-DCBC: 0.20 %
Related chlorinated compounds (total): ≤ 1.50 %
Process-related impurities:
3,5-Dichlorobenzoic acid: 1.00 %
3,5-Dichlorobenzoic anhydride: 1.00 %
Other specified impurities: ≤ 0.40 %
A full Certificate of Analysis (COA) is supplied with each batch.
Manufacturing, Safety and Global Supply
Advanced Manufacturing Through Qualified Partners
We work with qualified manufacturing partners whose production processes are optimized for:
High purity: Minimizing by-products and residual impurities.
Consistency: Stable performance from batch to batch in your processes.
Scalability: Supply from pilot-scale quantities to multi-ton commercial orders.
Rigorous Quality Control
Each batch of 3,5-DCBC is tested using:
Gas chromatography (GC) for purity and impurity profiling.
NMR spectroscopy for structural confirmation.
Karl Fischer titration for moisture content.
Safe Handling and International Logistics
3,5-DCBC is handled under strict safety and logistics procedures suitable for export operations.
UN classification: UN 3261, Class 8 (corrosive), “Corrosive solid, acidic, organic, n.o.s. (3,5-dichlorobenzoyl chloride)”
Packaging: UN-approved steel drums and IBC tanks (Intermediate Bulk Containers) suitable for international transport.
We can provide all supporting documentation required for safe, compliant import into your country.
Why Work with Royalchem?
Reliable supply chain: Over 20 years of experience in international chemical trade, supported by an ISO 9001:2015 certified quality system.
Technical support: A team experienced in agrochemical and pharmaceutical applications, ready to assist with specifications and technical assessments.
Competitive pricing: Efficient sourcing and optimized logistics allow us to offer high-quality products at competitive prices.
Sustainability focus: We promote responsible chemical management, including solvent recycling where possible and continuous improvement in energy efficiency.
Request Your 3,5-DCBC Quote
Royalchem delivers the quality, traceability and consistency that modern industrial processes require.
Our technical sales team is ready to support your projects.
Contact us to:
Request a detailed COA and technical data sheet
Discuss specific purity or impurity profile requirements
Receive a competitive quotation tailored to your volume and delivery terms
Visit https://www.royalchem-es.com/
or get in touch directly with our sales team for more information on 3,5-dichlorobenzoyl chloride (3,5-DCBC).