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1-(2-Hydroxyethyl)piperazine
1-(2-Hydroxyethyl)piperazine (HEP; N-(2-hydroxyethyl)piperazine; 1-piperazineethanol; 2-piperazin-1-ylethanol; CAS 103-76-4; EC 203-142-3) is a water-soluble, bifunctional piperazine (C₆H₁₄N₂O, molecular weight 130.19, boiling point ≈242–246 °C, density ≈1.06 g/cm³) supplied by Royalchem Spain at ≥99.5% purity. Combining a secondary-amine ring with a reactive hydroxyethyl group, it is a versatile intermediate for film-forming corrosion inhibitors, modified epoxy curing agents, polyurethane catalysts, specialty surfactants, amine-based gas-treatment absorbents (CO₂/H₂S removal), and pharmaceutical and agrochemical building blocks.
Product Description
1-(2-Hydroxyethyl)piperazine (HEP)
Water-Soluble Bifunctional Piperazine (1-Piperazineethanol) — Intermediate for Corrosion Inhibitors, Epoxy Curing Agents, Surfactants, PU Catalysts & Gas Treatment
CAS: 103-76-4 EC: 203-142-3 Assay: ≥ 99.5%
1-(2-Hydroxyethyl)piperazine (HEP; N-(2-hydroxyethyl)piperazine; 1-piperazineethanol; 2-piperazin-1-ylethanol; CAS 103-76-4) is a water-soluble, bifunctional piperazine that combines a secondary-amine ring with a reactive hydroxyethyl group. This dual reactivity makes it a versatile intermediate for film-forming corrosion inhibitors, modified epoxy curing agents, polyurethane catalysts, specialty surfactants, gas-treatment absorbents, and pharmaceutical and agrochemical building blocks. Royalchem Spain supplies it at ≥ 99.5% purity as a clear, colourless to light-yellow liquid, delivered from our Valladolid distribution hub by drum or IBC with COA and SDS for every batch.
Technical Specifications (COA Data)
| Assay (GC) | ≥ 99.5% |
| Appearance | Colourless to light-yellow clear liquid |
| Water (KF) | ≤ 0.3% |
| Colour (APHA / Hazen) | ≤ 30 |
| Molecular Weight | 130.19 g/mol |
| Boiling Point | ≈ 242–246 °C |
| Density (20 °C) | ≈ 1.06 g/cm³ |
*Regulatory: EINECS-listed (EC 203-142-3); supplied in line with EU REACH requirements; manufactured under ISO 9001. GHS — Danger: causes severe skin burns and eye damage (H314); may cause respiratory irritation (H335). A corrosive alkaline amino-alcohol that absorbs CO₂ from air and can corrode some metals. Shipped as a Class 8 corrosive substance (typically UN 2735, amines, liquid, corrosive, PG II/III) — confirm against the current SDS. Handle with full PPE (gloves, goggles/face shield) and good ventilation; nitrogen blanketing helps preserve colour. Always refer to the current SDS.
Chemical Structure
Key Properties
• Molecular Formula: C₆H₁₄N₂O
• Molecular Weight: 130.19
• Boiling Point: ≈ 242–246 °C
• Density (20 °C): ≈ 1.06 g/cm³
• Molecular Weight: 130.19
• Boiling Point: ≈ 242–246 °C
• Density (20 °C): ≈ 1.06 g/cm³
Main Applications
Corrosion Inhibitors & Gas Treatment
A building block for film-forming corrosion inhibitors used in water treatment and oil & gas, and a component of amine-based CO₂/H₂S absorbents for gas sweetening and desulfurisation.
Epoxy Curing Agents & PU Catalysts
A precursor to piperazine-based epoxy curing agents and modified polyamines, and an intermediate for polyurethane catalysts, giving good reactivity and water compatibility.
Surfactants, Pharma & Agro Intermediates
Used to make water-compatible specialty surfactants, and a versatile piperazine fragment for pharmaceutical and agrochemical synthesis and electronic chemicals.
Logistics & Packaging
Standard Packaging:
200 kg HDPE or steel drums, or IBC totes (approx. 1000 kg) — or to customer requirement. Distributed by Royalchem Spain from our Valladolid hub. Shelf life 24 months in original sealed packaging.
Storage Conditions:
Store in tightly closed containers in a cool, dry, well-ventilated area, away from acids, oxidising agents, and CO₂-laden air; nitrogen blanketing is recommended. A corrosive base — use compatible packaging and protect from moisture pick-up, as it is hygroscopic and absorbs carbon dioxide.