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Acetonitrile (MeCN, methyl cyanide, CAS 75-05-8) is the most widely used aprotic polar solvent in analytical and synthetic chemistry. Its low UV cut-off, low viscosity, high elution strength, and full miscibility with water make it the benchmark mobile-phase solvent for HPLC and LC-MS, while its strong solvating power suits a wide range of organic and pharmaceutical reactions. Royalchem supplies this high-purity HPLC/gradient grade at ≥ 99.9% as a clear, colourless liquid, delivered from our Valladolid distribution hub in suitable solvent packaging.
| Content (GC) | ≥ 99.9% |
| Appearance | Clear, colourless liquid |
| Moisture (H₂O) | ≤ 0.01% |
| Titratable Acidity (as H⁺) | ≤ 0.0008 meq/g |
| Titratable Alkalinity (as OH⁻) | ≤ 0.0006 meq/g |
| Residue after Evaporation | ≤ 1.0 ppm |
| Density (25 °C) | ≈ 0.786 g/cm³ |
The benchmark mobile-phase solvent for HPLC, UHPLC, and LC-MS, valued for its low UV cut-off, low viscosity, high elution strength, and clean baseline. Also used in spectrophotometry, fluorimetry, and as an extraction solvent.
A versatile aprotic reaction and recrystallisation solvent, used in DNA and peptide synthesis, API manufacturing, and as a two-carbon building block and intermediate (for example in vitamin B1 synthesis).
A high-dielectric electrolyte solvent for batteries, supercapacitors, and cyclic voltammetry; a ligand in inorganic chemistry; and a solvent for extraction, radiopharmaceutical (FDG) synthesis, and other specialty uses.
Standard Packaging:
4 L amber glass bottles, 160 kg steel drums, or ISO tank for bulk. Distributed by Royalchem Spain from our Valladolid hub. HPLC grade has a limited shelf life — use within the date on the label.
Storage Conditions:
Store in tightly closed containers in a cool, well-ventilated flammable-liquids store, away from heat, sparks, ignition sources, oxidising agents, and strong acids. Keep bonded and grounded; protect from light and moisture to preserve analytical quality.