High-Purity Pharmaceutical & Agrochemical Intermediate
| Product Name | Cyanamide (Hydrogen Cyanamide, Carbimide) |
| CAS Number | 420-04-2 |
| EINECS Number | 206-992-3 |
| Molecular Formula | CH₂N₂ (NH₂CN) |
| Structural Formula | |
| Molecular Weight | 42.04 g/mol |
| Purity | ≥95% (±2.4%) |
| Dicyandiamide Content | ≤2.0% |
| Water Insoluble Matter | ≤0.5% |
| Appearance | White crystals / Colorless to slightly yellow aqueous solution |
| Available Forms | 30% Solution | 50% Solution | ≥95% Crystals |
| Solubility | Highly soluble in water (775 g/L at 15°C), alcohols, ketones, ethers |
Cyanamide serves as a crucial building block in pharmaceutical manufacturing, offering unique reactivity for heterocyclic compound synthesis. Its bifunctional nature (containing both nucleophilic and electrophilic sites) makes it invaluable for creating complex drug molecules.
Key Pharmaceutical Syntheses:
Anti-ulcer Medications: Intermediate for cimetidine (H2 receptor antagonist)
Alcohol Dependence Therapy: Precursor for aldehyde dehydrogenase inhibitors used in Europe, Canada, and Japan
Antihypertensive Drugs: Key intermediate in minoxidil synthesis
Anthelmintic Agents: Used in albendazole, flubendazole, and mebendazole production
Anticancer Compounds: Intermediate for imatinib (tyrosine kinase inhibitor) and tirapazamine
Antiretroviral Drugs: Used in etravirine synthesis
Guanidine Derivatives: Creatine synthesis via reaction with sarcosine
Cyanamide is widely used as a dormancy-breaking agent (commercially known as Dormex) to stimulate uniform bud opening, early foliation, and synchronized flowering in deciduous fruit crops.
Key Agricultural Uses:
Fruit Cultivation: Promotes uniform bud break in grapes, kiwifruit, apples, peaches, blueberries, almonds, and pistachios
Yield Optimization: Compensates for insufficient chilling hours in warm climates
Harvest Timing: Enables earlier and more concentrated flowering for efficient harvesting
Essential raw material for synthesizing low-toxicity, broad-spectrum agrochemicals:
Fungicides: Carbendazim, benomyl, mepanipyrim
Herbicides: Chlorsulfuron, metsulfuron-methyl, tribenuron-methyl, hexazinone
Insecticides: Pirimicarb
50% aqueous solution used effectively in livestock farming to control salmonella, shigella, and flies in all development stages.
Key intermediate in melamine-formaldehyde resin production
Essential for high-performance polymer applications
Industrial adhesives and coating formulations
Primary precursor for dicyandiamide production
Flame retardant applications
Slow-release nitrogen fertilizers
Synthesis of guanidine salts and complexes
Pharmaceutical and chemical intermediate applications
Catalyst systems
Textile Industry: Dye intermediates and fixing agents
Water Treatment: Flocculant and coagulant synthesis
Rubber Industry: Synthetic rubber production
Fuel Additives: Stabilizers for fuels and lubricants
Steel Processing: Surface treatment and cleaning applications
Metal Finishing: Specialized cleaning formulations
Industrial Cleaning: Component in metal degreasing solutions
✅ REACH Compliant
✅ High Purity Guaranteed
✅ Multiple Forms Available: 30% solution, 50% solution, and crystalline grades
✅ Complete Documentation
✅ European Logistics
✅ Technical Support: Expert guidance on pharmaceutical and agrochemical applications
REACH Registration: Compliant for industrial and pharmaceutical uses
Industrial Use: Fully approved for chemical manufacturing and synthesis
ISO 9001:2015 Quality Management System
ISO 14001:2015 Environmental Management
Safety Data Sheet: Available in multiple languages (EN, ES)
Storage Requirements: Cool, dry conditions (2-8°C) away from acids and bases
Stability: Solutions stabilized with phosphate buffer to prevent self-condensation
